%OSDrive%\ProgramData\Microsoft\Windows Defender\Platform\* To work around this issue, open Group Policy, and then change the setting to "Allow" for the following path: Because of a change in the file path location in the latest update (Antimalware Client Version: 7.17123), many downloads are being blocked when AppLocker is enabled.It doesn't explain the reason behind the change, but points to the new location of files in the list of known issues: The file location change happens after installing the update KB4052623. The related driver files can be found under the folder C:\Windows\System32\drivers\wd, which were previously stored in the C:\Windows\System32\drivers folder. The files MsMpEng.exe and NisSrv.exe have been moved from C:\Program Files\Windows Defender to C:\ProgramData\Microsoft\Windows Defender\Platform\. The affected components include the antivirus engine MsMpEng.exe, the network filter service NisSrv.exe, and the appropriate drivers.
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